Dulaglutide half-life
Dulaglutide has an elimination half-life of about 4.7 days. Use the free calculator to plot how Dulaglutide levels rise and decay across your own doses.
Open Dulaglutide in the calculator
Reference data
- Half-life
- 4.7 days
- Route
- SC weekly
- Category
- GLP-1 & incretins
- Evidence
- Clinical
- Also known as
- Trulicity
FDA label: about 4.7 days.
How much Dulaglutide remains over time
For a single dose with first-order elimination, half of what remains is cleared every 4.7 days.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 4.7 days | 50% | 50% |
| 2 | 9.3 days | 25% | 75% |
| 3 | 14 days | 12.5% | 87.5% |
| 4 | 18.7 days | 6.25% | 93.75% |
| 5 | 23.3 days | 3.13% | 96.88% |
Dulaglutide FAQ
What is the half-life of Dulaglutide?
Dulaglutide has an elimination half-life of about 4.7 days (SC weekly). FDA label: about 4.7 days.
How long does Dulaglutide stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 23.3 days for Dulaglutide. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Dulaglutide reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 18.7 days to 23.3 days for Dulaglutide.
How reliable is this Dulaglutide half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.