Tesofensine half-life
Tesofensine has an elimination half-life of about 9.2 days. Use the free calculator to plot how Tesofensine levels rise and decay across your own doses.
Open Tesofensine in the calculator
Reference data
- Half-life
- 9.2 days
- Route
- Oral daily
- Category
- Metabolic & endocrine
- Evidence
- Limited
- Also known as
- NS2330
Non-peptide; clinical trials report about 9 days.
How much Tesofensine remains over time
For a single dose with first-order elimination, half of what remains is cleared every 9.2 days.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 9.2 days | 50% | 50% |
| 2 | 18.3 days | 25% | 75% |
| 3 | 27.5 days | 12.5% | 87.5% |
| 4 | 36.7 days | 6.25% | 93.75% |
| 5 | 45.8 days | 3.13% | 96.88% |
Tesofensine FAQ
What is the half-life of Tesofensine?
Tesofensine has an elimination half-life of about 9.2 days (Oral daily). Non-peptide; clinical trials report about 9 days.
How long does Tesofensine stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 45.8 days for Tesofensine. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Tesofensine reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 36.7 days to 45.8 days for Tesofensine.
How reliable is this Tesofensine half-life?
Evidence level: Limited. Based on early-phase human trials, small human studies, or animal pharmacokinetics only.