Teriparatide half-life
Teriparatide has an elimination half-life of about 1 h. Use the free calculator to plot how Teriparatide levels rise and decay across your own doses.
Open Teriparatide in the calculator
Reference data
- Half-life
- 1 h
- Route
- SC daily
- Category
- Metabolic & endocrine
- Evidence
- Clinical
- Also known as
- Forteo, PTH (1-34)
FDA label: about 1 hour after SC injection.
How much Teriparatide remains over time
For a single dose with first-order elimination, half of what remains is cleared every 1 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 1 h | 50% | 50% |
| 2 | 2 h | 25% | 75% |
| 3 | 3 h | 12.5% | 87.5% |
| 4 | 4 h | 6.25% | 93.75% |
| 5 | 5 h | 3.13% | 96.88% |
Teriparatide FAQ
What is the half-life of Teriparatide?
Teriparatide has an elimination half-life of about 1 h (SC daily). FDA label: about 1 hour after SC injection.
How long does Teriparatide stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 5 h for Teriparatide. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Teriparatide reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 4 h to 5 h for Teriparatide.
How reliable is this Teriparatide half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.