Pasireotide half-life
Pasireotide has an elimination half-life of about 12 h. Use the free calculator to plot how Pasireotide levels rise and decay across your own doses.
Open Pasireotide in the calculator
Reference data
- Half-life
- 12 h
- Route
- SC twice daily
- Category
- Metabolic & endocrine
- Evidence
- Clinical
- Also known as
- Signifor
Label: effective half-life of about 12 hours.
How much Pasireotide remains over time
For a single dose with first-order elimination, half of what remains is cleared every 12 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 12 h | 50% | 50% |
| 2 | 24 h | 25% | 75% |
| 3 | 36 h | 12.5% | 87.5% |
| 4 | 2 days | 6.25% | 93.75% |
| 5 | 2.5 days | 3.13% | 96.88% |
Pasireotide FAQ
What is the half-life of Pasireotide?
Pasireotide has an elimination half-life of about 12 h (SC twice daily). Label: effective half-life of about 12 hours.
How long does Pasireotide stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 2.5 days for Pasireotide. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Pasireotide reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 2 days to 2.5 days for Pasireotide.
How reliable is this Pasireotide half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.