Octreotide half-life
Octreotide has an elimination half-life of about 1.7 h. Use the free calculator to plot how Octreotide levels rise and decay across your own doses.
Open Octreotide in the calculator
Reference data
- Half-life
- 1.7 h
- Route
- SC
- Category
- Metabolic & endocrine
- Evidence
- Clinical
- Also known as
- Sandostatin
Immediate-release label: about 1.7 hours. LAR is release-limited.
How much Octreotide remains over time
For a single dose with first-order elimination, half of what remains is cleared every 1.7 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 1.7 h | 50% | 50% |
| 2 | 3.4 h | 25% | 75% |
| 3 | 5.1 h | 12.5% | 87.5% |
| 4 | 6.8 h | 6.25% | 93.75% |
| 5 | 8.5 h | 3.13% | 96.88% |
Octreotide FAQ
What is the half-life of Octreotide?
Octreotide has an elimination half-life of about 1.7 h (SC). Immediate-release label: about 1.7 hours. LAR is release-limited.
How long does Octreotide stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 8.5 h for Octreotide. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Octreotide reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 6.8 h to 8.5 h for Octreotide.
How reliable is this Octreotide half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.