Somatostatin half-life
Somatostatin has an elimination half-life of about 2 min. Use the free calculator to plot how Somatostatin levels rise and decay across your own doses.
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Reference data
- Half-life
- 2 min
- Route
- IV
- Category
- Metabolic & endocrine
- Evidence
- Clinical
- Also known as
- SST-14, GHIH
1–3 minutes in plasma.
How much Somatostatin remains over time
For a single dose with first-order elimination, half of what remains is cleared every 2 min.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 2 min | 50% | 50% |
| 2 | 4 min | 25% | 75% |
| 3 | 5 min | 12.5% | 87.5% |
| 4 | 7 min | 6.25% | 93.75% |
| 5 | 9 min | 3.13% | 96.88% |
Somatostatin FAQ
What is the half-life of Somatostatin?
Somatostatin has an elimination half-life of about 2 min (IV). 1–3 minutes in plasma.
How long does Somatostatin stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 9 min for Somatostatin. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Somatostatin reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 7 min to 9 min for Somatostatin.
How reliable is this Somatostatin half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.