PEG-MGF half-life
PEG-MGF has an elimination half-life of about 2 days. Use the free calculator to plot how PEG-MGF levels rise and decay across your own doses.
Open PEG-MGF in the calculator
Reference data
- Half-life
- 2 days
- Route
- SC / IM
- Category
- GH & IGF-1
- Evidence
- Anecdotal
- Also known as
- Pegylated mechano growth factor
No human PK; pegylation is assumed to extend it to days.
How much PEG-MGF remains over time
For a single dose with first-order elimination, half of what remains is cleared every 2 days.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 2 days | 50% | 50% |
| 2 | 4 days | 25% | 75% |
| 3 | 6 days | 12.5% | 87.5% |
| 4 | 8 days | 6.25% | 93.75% |
| 5 | 10 days | 3.13% | 96.88% |
PEG-MGF FAQ
What is the half-life of PEG-MGF?
PEG-MGF has an elimination half-life of about 2 days (SC / IM). No human PK; pegylation is assumed to extend it to days.
How long does PEG-MGF stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 10 days for PEG-MGF. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until PEG-MGF reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 8 days to 10 days for PEG-MGF.
How reliable is this PEG-MGF half-life?
Evidence level: Anecdotal. No published pharmacokinetic data; this is a community estimate and may be far off.