Somapacitan half-life
Somapacitan has an elimination half-life of about 2.5 days (range 2–3 days). Use the free calculator to plot how Somapacitan levels rise and decay across your own doses.
Open Somapacitan in the calculator
Reference data
- Half-life
- 2.5 days (range 2–3 days)
- Route
- SC weekly
- Category
- GH & IGF-1
- Evidence
- Clinical
- Also known as
- Sogroya
Label: about 2–3 days.
How much Somapacitan remains over time
For a single dose with first-order elimination, half of what remains is cleared every 2.5 days.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 2.5 days | 50% | 50% |
| 2 | 5 days | 25% | 75% |
| 3 | 7.5 days | 12.5% | 87.5% |
| 4 | 10 days | 6.25% | 93.75% |
| 5 | 12.5 days | 3.13% | 96.88% |
Somapacitan FAQ
What is the half-life of Somapacitan?
Somapacitan has an elimination half-life of about 2.5 days (range 2–3 days) (SC weekly). Label: about 2–3 days.
How long does Somapacitan stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 12.5 days for Somapacitan. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Somapacitan reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 10 days to 12.5 days for Somapacitan.
How reliable is this Somapacitan half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.