Ipamorelin half-life
Ipamorelin has an elimination half-life of about 2 h. Use the free calculator to plot how Ipamorelin levels rise and decay across your own doses.
Open Ipamorelin in the calculator
Reference data
- Half-life
- 2 h
- Route
- SC / IV
- Category
- GH secretagogues
- Evidence
- Limited
- Also known as
- NNC 26-0161
Human IV PK study: terminal half-life about 2 hours.
How much Ipamorelin remains over time
For a single dose with first-order elimination, half of what remains is cleared every 2 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 2 h | 50% | 50% |
| 2 | 4 h | 25% | 75% |
| 3 | 6 h | 12.5% | 87.5% |
| 4 | 8 h | 6.25% | 93.75% |
| 5 | 10 h | 3.13% | 96.88% |
Ipamorelin FAQ
What is the half-life of Ipamorelin?
Ipamorelin has an elimination half-life of about 2 h (SC / IV). Human IV PK study: terminal half-life about 2 hours.
How long does Ipamorelin stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 10 h for Ipamorelin. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Ipamorelin reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 8 h to 10 h for Ipamorelin.
How reliable is this Ipamorelin half-life?
Evidence level: Limited. Based on early-phase human trials, small human studies, or animal pharmacokinetics only.