Sermorelin half-life
Sermorelin has an elimination half-life of about 12 min (range 10–20 min). Use the free calculator to plot how Sermorelin levels rise and decay across your own doses.
Open Sermorelin in the calculator
Reference data
- Half-life
- 12 min (range 10–20 min)
- Route
- SC
- Category
- GH secretagogues
- Evidence
- Clinical
- Also known as
- GRF 1-29, Geref
Former label: about 11–12 minutes.
How much Sermorelin remains over time
For a single dose with first-order elimination, half of what remains is cleared every 12 min.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 12 min | 50% | 50% |
| 2 | 24 min | 25% | 75% |
| 3 | 36 min | 12.5% | 87.5% |
| 4 | 48 min | 6.25% | 93.75% |
| 5 | 1 h | 3.13% | 96.88% |
Sermorelin FAQ
What is the half-life of Sermorelin?
Sermorelin has an elimination half-life of about 12 min (range 10–20 min) (SC). Former label: about 11–12 minutes.
How long does Sermorelin stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 1 h for Sermorelin. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Sermorelin reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 48 min to 1 h for Sermorelin.
How reliable is this Sermorelin half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.