Ibutamoren half-life
Ibutamoren has an elimination half-life of about 5 h (range 4–6 h). Use the free calculator to plot how Ibutamoren levels rise and decay across your own doses.
Open Ibutamoren in the calculator
Reference data
- Half-life
- 5 h (range 4–6 h)
- Route
- Oral daily
- Category
- GH secretagogues
- Evidence
- Limited
- Also known as
- MK-677, MK-0677
Non-peptide oral secretagogue; GH elevation outlasts plasma levels (~24 h).
How much Ibutamoren remains over time
For a single dose with first-order elimination, half of what remains is cleared every 5 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 5 h | 50% | 50% |
| 2 | 10 h | 25% | 75% |
| 3 | 15 h | 12.5% | 87.5% |
| 4 | 20 h | 6.25% | 93.75% |
| 5 | 25 h | 3.13% | 96.88% |
Ibutamoren FAQ
What is the half-life of Ibutamoren?
Ibutamoren has an elimination half-life of about 5 h (range 4–6 h) (Oral daily). Non-peptide oral secretagogue; GH elevation outlasts plasma levels (~24 h).
How long does Ibutamoren stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 25 h for Ibutamoren. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Ibutamoren reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 20 h to 25 h for Ibutamoren.
How reliable is this Ibutamoren half-life?
Evidence level: Limited. Based on early-phase human trials, small human studies, or animal pharmacokinetics only.