Glucagon half-life
Glucagon has an elimination half-life of about 30 min. Use the free calculator to plot how Glucagon levels rise and decay across your own doses.
Open Glucagon in the calculator
Reference data
- Half-life
- 30 min
- Route
- SC / IM / intranasal
- Category
- Metabolic & endocrine
- Evidence
- Clinical
- Also known as
- GlucaGen, Gvoke, Baqsimi
Label (SC): about 30 minutes.
How much Glucagon remains over time
For a single dose with first-order elimination, half of what remains is cleared every 30 min.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 30 min | 50% | 50% |
| 2 | 1 h | 25% | 75% |
| 3 | 1.5 h | 12.5% | 87.5% |
| 4 | 2 h | 6.25% | 93.75% |
| 5 | 2.5 h | 3.13% | 96.88% |
Glucagon FAQ
What is the half-life of Glucagon?
Glucagon has an elimination half-life of about 30 min (SC / IM / intranasal). Label (SC): about 30 minutes.
How long does Glucagon stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 2.5 h for Glucagon. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Glucagon reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 2 h to 2.5 h for Glucagon.
How reliable is this Glucagon half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.