MOTS-c half-life
MOTS-c has an elimination half-life of about 30 min. Use the free calculator to plot how MOTS-c levels rise and decay across your own doses.
Reference data
- Half-life
- 30 min
- Route
- SC
- Category
- Longevity & mitochondrial
- Evidence
- Anecdotal
- Also known as
- Mitochondrial ORF of the 12S rRNA type-c
No human PK; estimate.
How much MOTS-c remains over time
For a single dose with first-order elimination, half of what remains is cleared every 30 min.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 30 min | 50% | 50% |
| 2 | 1 h | 25% | 75% |
| 3 | 1.5 h | 12.5% | 87.5% |
| 4 | 2 h | 6.25% | 93.75% |
| 5 | 2.5 h | 3.13% | 96.88% |
MOTS-c FAQ
What is the half-life of MOTS-c?
MOTS-c has an elimination half-life of about 30 min (SC). No human PK; estimate.
How long does MOTS-c stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 2.5 h for MOTS-c. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until MOTS-c reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 2 h to 2.5 h for MOTS-c.
How reliable is this MOTS-c half-life?
Evidence level: Anecdotal. No published pharmacokinetic data; this is a community estimate and may be far off.