Glutathione half-life
Glutathione has an elimination half-life of about 10 min. Use the free calculator to plot how Glutathione levels rise and decay across your own doses.
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Reference data
- Half-life
- 10 min
- Route
- IV / IM
- Category
- Longevity & mitochondrial
- Evidence
- Limited
- Also known as
- GSH, L-glutathione
Human IV data: plasma half-life of about 10 minutes.
How much Glutathione remains over time
For a single dose with first-order elimination, half of what remains is cleared every 10 min.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 10 min | 50% | 50% |
| 2 | 20 min | 25% | 75% |
| 3 | 31 min | 12.5% | 87.5% |
| 4 | 41 min | 6.25% | 93.75% |
| 5 | 51 min | 3.13% | 96.88% |
Glutathione FAQ
What is the half-life of Glutathione?
Glutathione has an elimination half-life of about 10 min (IV / IM). Human IV data: plasma half-life of about 10 minutes.
How long does Glutathione stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 51 min for Glutathione. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Glutathione reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 41 min to 51 min for Glutathione.
How reliable is this Glutathione half-life?
Evidence level: Limited. Based on early-phase human trials, small human studies, or animal pharmacokinetics only.