Melanotan II half-life
Melanotan II has an elimination half-life of about 1 h. Use the free calculator to plot how Melanotan II levels rise and decay across your own doses.
Open Melanotan II in the calculator
Reference data
- Half-life
- 1 h
- Route
- SC
- Category
- Melanocortins
- Evidence
- Limited
- Also known as
- MT-II, MT2, Melanotan 2
Rodent data only (about 1 hour); no published human PK.
How much Melanotan II remains over time
For a single dose with first-order elimination, half of what remains is cleared every 1 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 1 h | 50% | 50% |
| 2 | 2 h | 25% | 75% |
| 3 | 3 h | 12.5% | 87.5% |
| 4 | 4 h | 6.25% | 93.75% |
| 5 | 5 h | 3.13% | 96.88% |
Melanotan II FAQ
What is the half-life of Melanotan II?
Melanotan II has an elimination half-life of about 1 h (SC). Rodent data only (about 1 hour); no published human PK.
How long does Melanotan II stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 5 h for Melanotan II. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Melanotan II reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 4 h to 5 h for Melanotan II.
How reliable is this Melanotan II half-life?
Evidence level: Limited. Based on early-phase human trials, small human studies, or animal pharmacokinetics only.