Bremelanotide half-life

Bremelanotide has an elimination half-life of about 2.7 h. Use the free calculator to plot how Bremelanotide levels rise and decay across your own doses.

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Reference data

Half-life
2.7 h
Route
SC as needed
Category
Melanocortins
Evidence
Clinical
Also known as
PT-141, Vyleesi

FDA label: about 2.7 hours.

How much Bremelanotide remains over time

For a single dose with first-order elimination, half of what remains is cleared every 2.7 h.

Half-livesTime after doseRemainingEliminated
12.7 h50%50%
25.4 h25%75%
38.1 h12.5%87.5%
410.8 h6.25%93.75%
513.5 h3.13%96.88%

Bremelanotide FAQ

What is the half-life of Bremelanotide?

Bremelanotide has an elimination half-life of about 2.7 h (SC as needed). FDA label: about 2.7 hours.

How long does Bremelanotide stay in your system?

With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 13.5 h for Bremelanotide. Individual clearance varies with dose, injection site, kidney function and other factors.

How long until Bremelanotide reaches steady state?

With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 10.8 h to 13.5 h for Bremelanotide.

How reliable is this Bremelanotide half-life?

Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.

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