Insulin glulisine half-life
Insulin glulisine has an elimination half-life of about 42 min. Use the free calculator to plot how Insulin glulisine levels rise and decay across your own doses.
Open Insulin glulisine in the calculator
Reference data
- Half-life
- 42 min
- Route
- SC
- Category
- Insulins
- Evidence
- Clinical
- Also known as
- Apidra
Label: about 42 minutes after SC injection.
How much Insulin glulisine remains over time
For a single dose with first-order elimination, half of what remains is cleared every 42 min.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 42 min | 50% | 50% |
| 2 | 1.4 h | 25% | 75% |
| 3 | 2.1 h | 12.5% | 87.5% |
| 4 | 2.8 h | 6.25% | 93.75% |
| 5 | 3.5 h | 3.13% | 96.88% |
Insulin glulisine FAQ
What is the half-life of Insulin glulisine?
Insulin glulisine has an elimination half-life of about 42 min (SC). Label: about 42 minutes after SC injection.
How long does Insulin glulisine stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 3.5 h for Insulin glulisine. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Insulin glulisine reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 2.8 h to 3.5 h for Insulin glulisine.
How reliable is this Insulin glulisine half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.