Insulin detemir half-life
Insulin detemir has an elimination half-life of about 7 h (range 5–7 h). Use the free calculator to plot how Insulin detemir levels rise and decay across your own doses.
Open Insulin detemir in the calculator
Reference data
- Half-life
- 7 h (range 5–7 h)
- Route
- SC
- Category
- Insulins
- Evidence
- Clinical
- Also known as
- Levemir
Label: 5–7 hours depending on dose.
How much Insulin detemir remains over time
For a single dose with first-order elimination, half of what remains is cleared every 7 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 7 h | 50% | 50% |
| 2 | 14 h | 25% | 75% |
| 3 | 21 h | 12.5% | 87.5% |
| 4 | 28 h | 6.25% | 93.75% |
| 5 | 35 h | 3.13% | 96.88% |
Insulin detemir FAQ
What is the half-life of Insulin detemir?
Insulin detemir has an elimination half-life of about 7 h (range 5–7 h) (SC). Label: 5–7 hours depending on dose.
How long does Insulin detemir stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 35 h for Insulin detemir. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Insulin detemir reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 28 h to 35 h for Insulin detemir.
How reliable is this Insulin detemir half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.