Triptorelin half-life
Triptorelin has an elimination half-life of about 2.8 h. Use the free calculator to plot how Triptorelin levels rise and decay across your own doses.
Open Triptorelin in the calculator
Reference data
- Half-life
- 2.8 h
- Route
- IM / SC
- Category
- Reproductive & hormonal
- Evidence
- Clinical
- Also known as
- Trelstar, Triptodur, Decapeptyl
Immediate-release, healthy volunteers: about 2.8 hours. Depots are release-limited.
How much Triptorelin remains over time
For a single dose with first-order elimination, half of what remains is cleared every 2.8 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 2.8 h | 50% | 50% |
| 2 | 5.6 h | 25% | 75% |
| 3 | 8.4 h | 12.5% | 87.5% |
| 4 | 11.2 h | 6.25% | 93.75% |
| 5 | 14 h | 3.13% | 96.88% |
Triptorelin FAQ
What is the half-life of Triptorelin?
Triptorelin has an elimination half-life of about 2.8 h (IM / SC). Immediate-release, healthy volunteers: about 2.8 hours. Depots are release-limited.
How long does Triptorelin stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 14 h for Triptorelin. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Triptorelin reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 11.2 h to 14 h for Triptorelin.
How reliable is this Triptorelin half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.