Ganirelix half-life
Ganirelix has an elimination half-life of about 16 h (range 13–16 h). Use the free calculator to plot how Ganirelix levels rise and decay across your own doses.
Open Ganirelix in the calculator
Reference data
- Half-life
- 16 h (range 13–16 h)
- Route
- SC daily
- Category
- Reproductive & hormonal
- Evidence
- Clinical
- Also known as
- Fyremadel, Orgalutran
Label: about 13–16 hours.
How much Ganirelix remains over time
For a single dose with first-order elimination, half of what remains is cleared every 16 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 16 h | 50% | 50% |
| 2 | 32 h | 25% | 75% |
| 3 | 2 days | 12.5% | 87.5% |
| 4 | 2.7 days | 6.25% | 93.75% |
| 5 | 3.3 days | 3.13% | 96.88% |
Ganirelix FAQ
What is the half-life of Ganirelix?
Ganirelix has an elimination half-life of about 16 h (range 13–16 h) (SC daily). Label: about 13–16 hours.
How long does Ganirelix stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 3.3 days for Ganirelix. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Ganirelix reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 2.7 days to 3.3 days for Ganirelix.
How reliable is this Ganirelix half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.