Gonadorelin half-life
Gonadorelin has an elimination half-life of about 18 min (range 10–40 min). Use the free calculator to plot how Gonadorelin levels rise and decay across your own doses.
Open Gonadorelin in the calculator
Reference data
- Half-life
- 18 min (range 10–40 min)
- Route
- SC / IV
- Category
- Reproductive & hormonal
- Evidence
- Clinical
- Also known as
- GnRH, Factrel, LHRH
Label: terminal half-life 10–40 minutes.
How much Gonadorelin remains over time
For a single dose with first-order elimination, half of what remains is cleared every 18 min.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 18 min | 50% | 50% |
| 2 | 36 min | 25% | 75% |
| 3 | 54 min | 12.5% | 87.5% |
| 4 | 1.2 h | 6.25% | 93.75% |
| 5 | 1.5 h | 3.13% | 96.88% |
Gonadorelin FAQ
What is the half-life of Gonadorelin?
Gonadorelin has an elimination half-life of about 18 min (range 10–40 min) (SC / IV). Label: terminal half-life 10–40 minutes.
How long does Gonadorelin stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 1.5 h for Gonadorelin. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Gonadorelin reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 1.2 h to 1.5 h for Gonadorelin.
How reliable is this Gonadorelin half-life?
Evidence level: Clinical. Based on a regulatory label or well-replicated human pharmacokinetic data.