Kinetic

BPC-157 vs TB-500 half-life

BPC-157 has an elimination half-life of about 30 min; TB-500 has about 1.5 h. BPC-157 is a synthetic 15-amino-acid fragment of a gastric protein; TB-500 is a synthetic fragment related to thymosin beta-4. Both are research peptides with little human pharmacokinetic data, so their half-lives are rough estimates.

Side by side

BPC-157TB-500
Half-life30 min (range 8–30 min)1.5 h
RouteSC / oralSC
CategoryHealing & repairHealing & repair
EvidenceLimitedAnecdotal
Remaining after 24 hours<0.01%<0.01%
Remaining after 7 days<0.01%<0.01%
~97% cleared (5 half-lives)2.5 h7.5 h
Steady state (4-5 half-lives)2 h to 2.5 h6 h to 7.5 h

Single-dose decay

Share of one dose remaining over time, assuming first-order elimination. Dashed lines mark each half-life.

BPC-157 vs TB-500 single-dose decay 0% 25% 50% 75% 100% 0 2 h 4 h 6 h 8 h

BPC-157 (t½ 30 min) TB-500 (t½ 1.5 h)

BPC-157: Rat/dog PK only: plasma half-life under 30 minutes. Many protocols assume ~4 h; adjust if preferred. TB-500: Synthetic Tβ4 fragment with no published human PK; uses full-length Tβ4 data.

Model BPC-157 doses Model TB-500 doses

FAQ

Which lasts longer, BPC-157 or TB-500?

TB-500 lasts longer. Its half-life is about 1.5 h, versus 30 min for BPC-157, roughly 3 times longer.

How long do BPC-157 and TB-500 stay in your system?

With first-order elimination, about 97% of a single dose is cleared after five half-lives: roughly 2.5 h for BPC-157 and 7.5 h for TB-500. Individual clearance varies.

How long until BPC-157 and TB-500 reach steady state?

With consistent repeated dosing, levels approach steady state after 4 to 5 half-lives: about 2 h to 2.5 h for BPC-157, and 6 h to 7.5 h for TB-500.

How reliable are these half-lives?

BPC-157: Limited evidence. TB-500: Anecdotal evidence. Anecdotal values are community estimates and may be far off.

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