BPC-157 vs GHK-Cu half-life
BPC-157 has an elimination half-life of about 30 min; GHK-Cu has about 1 h. GHK-Cu is a naturally occurring copper-binding tripeptide widely used in cosmetics; BPC-157 is a synthetic gastric-protein fragment. Both are researched for tissue repair, and both are estimated to clear from blood quickly.
Side by side
| BPC-157 | GHK-Cu | |
|---|---|---|
| Half-life | 30 min (range 8–30 min) | 1 h |
| Route | SC / oral | SC / topical |
| Category | Healing & repair | Healing & repair |
| Evidence | Limited | Anecdotal |
| Remaining after 24 hours | <0.01% | <0.01% |
| Remaining after 7 days | <0.01% | <0.01% |
| ~97% cleared (5 half-lives) | 2.5 h | 5 h |
| Steady state (4-5 half-lives) | 2 h to 2.5 h | 4 h to 5 h |
Single-dose decay
Share of one dose remaining over time, assuming first-order elimination. Dashed lines mark each half-life.
BPC-157 (t½ 30 min) GHK-Cu (t½ 1 h)
BPC-157: Rat/dog PK only: plasma half-life under 30 minutes. Many protocols assume ~4 h; adjust if preferred. GHK-Cu: No human injectable PK; short-lived in plasma.
FAQ
Which lasts longer, BPC-157 or GHK-Cu?
GHK-Cu lasts longer. Its half-life is about 1 h, versus 30 min for BPC-157, roughly 2 times longer.
How long do BPC-157 and GHK-Cu stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives: roughly 2.5 h for BPC-157 and 5 h for GHK-Cu. Individual clearance varies.
How long until BPC-157 and GHK-Cu reach steady state?
With consistent repeated dosing, levels approach steady state after 4 to 5 half-lives: about 2 h to 2.5 h for BPC-157, and 4 h to 5 h for GHK-Cu.
How reliable are these half-lives?
BPC-157: Limited evidence. GHK-Cu: Anecdotal evidence. Anecdotal values are community estimates and may be far off.