Thymosin beta-4 half-life
Thymosin beta-4 has an elimination half-life of about 1.5 h (range 30 min–2.1 h). Use the free calculator to plot how Thymosin beta-4 levels rise and decay across your own doses.
Open Thymosin beta-4 in the calculator
Reference data
- Half-life
- 1.5 h (range 30 min–2.1 h)
- Route
- IV / SC
- Category
- Healing & repair
- Evidence
- Limited
- Also known as
- Tβ4, TB4, Timbetasin
Phase 1 (IV, recombinant): terminal half-life 0.5–2.1 hours.
How much Thymosin beta-4 remains over time
For a single dose with first-order elimination, half of what remains is cleared every 1.5 h.
| Half-lives | Time after dose | Remaining | Eliminated |
|---|---|---|---|
| 1 | 1.5 h | 50% | 50% |
| 2 | 3 h | 25% | 75% |
| 3 | 4.5 h | 12.5% | 87.5% |
| 4 | 6 h | 6.25% | 93.75% |
| 5 | 7.5 h | 3.13% | 96.88% |
Thymosin beta-4 FAQ
What is the half-life of Thymosin beta-4?
Thymosin beta-4 has an elimination half-life of about 1.5 h (range 30 min–2.1 h) (IV / SC). Phase 1 (IV, recombinant): terminal half-life 0.5–2.1 hours.
How long does Thymosin beta-4 stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives, roughly 7.5 h for Thymosin beta-4. Individual clearance varies with dose, injection site, kidney function and other factors.
How long until Thymosin beta-4 reaches steady state?
With consistent repeated dosing, levels approach steady state after about 4 to 5 half-lives, or roughly 6 h to 7.5 h for Thymosin beta-4.
How reliable is this Thymosin beta-4 half-life?
Evidence level: Limited. Based on early-phase human trials, small human studies, or animal pharmacokinetics only.