GHRP-2 vs GHRP-6 half-life
GHRP-2 has an elimination half-life of about 30 min; GHRP-6 has about 30 min. Both are first-generation growth hormone releasing peptides acting on the ghrelin receptor. GHRP-2 is generally reported as the stronger GH releaser, GHRP-6 as the stronger appetite stimulant.
Side by side
| GHRP-2 | GHRP-6 | |
|---|---|---|
| Half-life | 30 min (range 15 min–1 h) | 30 min (range 15 min–1 h) |
| Route | SC | SC |
| Category | GH secretagogues | GH secretagogues |
| Evidence | Limited | Limited |
| Remaining after 24 hours | <0.01% | <0.01% |
| Remaining after 7 days | <0.01% | <0.01% |
| ~97% cleared (5 half-lives) | 2.5 h | 2.5 h |
| Steady state (4-5 half-lives) | 2 h to 2.5 h | 2 h to 2.5 h |
Single-dose decay
Share of one dose remaining over time, assuming first-order elimination. Dashed lines mark each half-life.
GHRP-2 (t½ 30 min) GHRP-6 (t½ 30 min)
GHRP-2: Short plasma half-life in human studies (roughly 15–60 minutes). GHRP-6: Sparse human PK; short plasma half-life.
FAQ
Which lasts longer, GHRP-2 or GHRP-6?
GHRP-2 and GHRP-6 have similar half-lives: about 30 min and 30 min.
How long do GHRP-2 and GHRP-6 stay in your system?
With first-order elimination, about 97% of a single dose is cleared after five half-lives: roughly 2.5 h for GHRP-2 and 2.5 h for GHRP-6. Individual clearance varies.
How long until GHRP-2 and GHRP-6 reach steady state?
With consistent repeated dosing, levels approach steady state after 4 to 5 half-lives: about 2 h to 2.5 h for GHRP-2, and 2 h to 2.5 h for GHRP-6.
How reliable are these half-lives?
GHRP-2: Limited evidence. GHRP-6: Limited evidence. Anecdotal values are community estimates and may be far off.